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Mutlu, Gokhan M.
One or more keywords matched the following properties of Mutlu, Gokhan M.
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keywords Particulate Matter
overview Dr. Mutlu is Professor of Medicine and Chief of the Section of Pulmonary and Critical Care Medicine at the University of Chicago. He is also the principal investigator/director of the NIH T32 Research training in respiratory biology. Dr. Mutlu's research focuses on the mechanisms of acute lung injury, and pulmonary fibrosis. Specifically, his laboratory is interested in understanding the role of macrophage and fibroblast metabolism including mitochondria in the pathogenesis of acute lung injury and pulmonary fibrosis. Dr. Mutlu's laboratory has extensive expertise with in vitro cell based methods including bioenergetics and in vivo models of acute lung injury (influenza, LPS, bacterial pneumonia and particulate matter) and pulmonary fibrosis (bleomycin).
One or more keywords matched the following items that are connected to Mutlu, Gokhan M.
Item TypeName
Academic Article Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution.
Academic Article Linking air pollution exposure with thrombosis.
Academic Article Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice.
Academic Article Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms.
Academic Article Proapoptotic Noxa is required for particulate matter-induced cell death and lung inflammation.
Academic Article p53 mediates particulate matter-induced alveolar epithelial cell mitochondria-regulated apoptosis.
Academic Article ß2-Adrenergic agonists augment air pollution-induced IL-6 release and thrombosis.
Academic Article Sequestration of mitochondrial iron by silica particle initiates a biological effect.
Academic Article Particulate matter Air Pollution induces hypermethylation of the p16 promoter Via a mitochondrial ROS-JNK-DNMT1 pathway.
Academic Article Update in environmental and occupational medicine 2010.
Academic Article Update in environmental and occupational medicine 2009.
Academic Article Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway.
Academic Article Airborne particulate matter inhibits alveolar fluid reabsorption in mice via oxidant generation.
Academic Article Letter by Mutlu and Budinger Regarding Article, "Particulate Matter Exposure and Stress Hormone Levels: A Randomized, Double-Blind, Crossover Trial of Air Purification".
Academic Article Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis.
Academic Article Inhalational exposure to particulate matter air pollution alters the composition of the gut microbiome.
Academic Article Particulate Matter Air Pollution: Effects on the Cardiovascular System.
Grant Particulate matter-induced changes in DNA methylome and transcriptome
Academic Article Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response.
Academic Article The Airway Epithelial Response to Air Pollution: It's Not Just Inflammation.
Grant Role of alveolar macrophages in particulate matter-induced cardiopulmonary disease
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  • Particulate Matter